12 Best Design & Artwork Approval Software for Manufacturers
May 20, 2025
Are you looking for the best design and artwork approval software to streamline your manufacturing process?
As manufacturers face increasing pressure to accelerate product launches and maintain brand consistency, the need for reliable artwork approval solutions has never been greater.
To help you stay ahead, we’ve rounded up the 12 best artwork approval software manufacturers should consider.
Let’s dive in!
Streamline Design Workflows: Top 12 Artwork Approval Software for Manufacturers
Here are the top 12 artwork approval software and their key features.
1. Signify
Signify is an AI agent for compliance that automates and streamlines regulatory processes, helping manufacturers stay ahead of complex requirements.
Built specifically for consumer goods industries like:
OTC Healthcare,
And others,
Signify reduces the administrative burden of compliance while improving accuracy and operational transparency.
By leveraging advanced AI technology, Signify proactively monitors regulations, evaluates conformity, and manages documentation to ensure your products meet FDA, USDA, ISO, FSMA, and over 1,000 other global regulatory frameworks.
Signify’s automated workflows are especially valuable for artwork validation and labeling compliance, in which even small errors can lead to costly delays or regulatory setbacks.
Our platform streamlines the entire artwork lifecycle, ensuring that every visual and textual asset is accurate, version-controlled, and fully compliant.
With Signify, this process is reduced to 8 to 17 hours per month, cutting review time by up to 90%.
Instead of spending hours manually checking spelling, grammar, formatting, and regulatory compliance, teams can now process labels in minutes, with structured results and clear next steps automatically generated.
The impact is immediate as teams reduce manual effort, streamline approval cycles, and eliminate common compliance bottlenecks to enable faster and more accurate product launches.
Key Features
Automated Labeling Compliance: Validate product labels quickly against regulatory requirements to minimize revision cycles and ensure compliance before launch.
Inspect Label Elements Automatically: Evaluate claims, warnings, ingredient lists, allergen declarations, and formatting against applicable regulations to ensure full compliance.
Reduce Costly Label Revisions: Detect non-compliant elements early in the design process to prevent delays and avoid expensive rework.
Artwork and Packaging Accuracy: Ensure packaging artwork meets brand guidelines and regulatory standards across markets and formats.
Automated Conformity Assessments: Use AI to review policies, procedures, and documentation, identifying gaps in minutes instead of weeks.
Compliance Smart Checklists: Turn complex regulations into easy-to-follow checklists that help teams track and close compliance gaps efficiently.
Proactive Regulatory Intelligence: Stay updated with continuous scans and alerts that notify you of relevant regulatory changes.
Global Compliance Management: Consolidate and harmonize regulatory requirements across markets, eliminating redundant efforts.
Regulatory Risk Tracker: Monitor and manage critical compliance risks before they escalate, helping you stay proactive.
Supplier Verification: Confirm that your suppliers meet compliance and sourcing standards, ensuring ethical and safe supply chains.
Document Traceability: Create traceability matrices linking regulations to supporting evidence, streamlining audits and certification prep.
Third-Party Certification Streamlining: Automate assessments and generate audit-ready documentation for faster certification readiness.
Regulatory Monitoring: Track regulatory changes impacting your categories and markets, with early alerts to reduce risk.
Defensible Audit Trails: Maintain a comprehensive, timestamped record of compliance activities for stronger governance and audit support.
Remediation Guidance: Get step-by-step recommendations to resolve compliance issues quickly and confidently.
2. BarTender
BarTender by Seagull Scientific is a label design and printing software that enables businesses to create, automate, and manage barcode labels, RFID tags, and documents across various industries.
With its design tools and integration capabilities, BarTender ensures compliance with industry standards, streamlines operations, and enhances supply chain efficiency.
Key Features
FIC and FDA Compliant Templates: Supports standardized label layouts aligned with EU FIC & FDA regulations, helping ensure consistent allergen and ingredient presentation.
Data Integration: Connects to ERP and production systems to auto-fill labels with up-to-date ingredients, allergens, and nutritional info.
Allergen Highlighting: Allows visual emphasis of allergens using custom text styles to meet labeling visibility requirements.
Multilingual Support: Enables creation of labels in multiple languages from a single template to meet international compliance needs.
3. Artwork Flow
Artwork Flow is an AI-powered artwork management platform streamlining packaging design, labeling compliance, and creative collaboration for manufacturers and consumer brands.
It offers features such as automated proofing, customizable workflows, and digital asset management to accelerate product launches while ensuring regulatory and brand consistency.
Key Features
Automated Proofing Workflows: Streamlines artwork review cycles with automated proofing tools, helping teams catch errors early and reduce approval delays.
Digital Asset & Version Management: Centralizes artwork files and version history, making it easier to track changes and maintain consistent, compliant packaging.
Regulatory Compliance Tracking: Embeds compliance checks into the review process to support market-specific labeling standards and reduce non-compliance risks.
Collaborative Annotation Tools: Enables real-time collaboration and markup on artwork files, improving clarity and alignment across teams and suppliers.
4. Esko
Esko provides software solutions that streamline packaging design, artwork approval, and production workflows for brand owners, retailers, and packaging manufacturers.
Its product suite includes tools for structural design (ArtiosCAD), 3D visualization (Studio), artwork management (WebCenter), and prepress automation, supporting compliance and accelerating time-to-market.
Key Features
Centralized Artwork Management: Provides a platform for managing packaging artwork, helping teams work from approved versions and reducing the risk of non-compliance.
Visual Review and Annotation: Offers a 3D environment for sharing, annotating, and approving artwork, improving review accuracy, and helping spot regulatory issues early.
Compliance Tracking with Version Control: Maintains audit trails and version histories, supporting traceability and documentation for internal reviews and external audits.
Digital Asset Management: Organizes creative assets to ensure that only compliant, up-to-date artwork is used in production.
5. R-stream
R-stream is a label artwork management platform that streamlines packaging design and compliance processes for manufacturers in industries like chemicals, food & beverage, and cosmetics.
It offers automation tools, centralized asset management, and integration capabilities to enhance efficiency and ensure regulatory adherence throughout the artwork lifecycle.
Key Features
End-to-End Workflow Automation: Automates the label artwork process, from creation to approval and archiving, ensuring all compliance steps are consistently followed.
Integrated Compliance Checks: Includes built-in checks and updates based on current regulations, helping reduce the risk of non-compliant packaging.
Centralized Version Control: Stores all artwork versions in one place to ensure traceability, prevent errors, and support regulatory audits.
Expert Review & DTP Services: Provides professional desktop publishing and regulatory reviews by specialists to ensure artwork meets compliance and branding requirements.
6. Kallik
Kallik is a cloud-based artwork and labeling management platform for regulated industries such as pharmaceuticals, cosmetics, and food and beverage.
Its Veraciti™ solution automates the creation, approval, and management of packaging and labeling assets, ensuring compliance with global regulatory standards.
Key Features
Automated Compliance Checks: Validates artwork and labeling against current regulations, helping reduce manual reviews and avoid compliance errors.
Centralized Asset Management: Stores all artwork files in a repository with version control and audit trails to support traceability and approval accuracy.
Collaborative Review Workflows: Enables real-time commenting and approvals across teams and partners, improving communication and speeding up sign-offs.
End-to-End Lifecycle Management: Covers the artwork process, from creation to archiving, ensuring control, visibility, and compliance at every stage.
7. Karomi
Karomi is a cloud-based platform that streamlines the packaging artwork lifecycle for FMCG, pharmaceutical, and cosmetics companies.
It centralizes content creation, approval workflows, and compliance checks to help brands reduce errors, accelerate time-to-market, and maintain regulatory standards.
Key Features
Automated Review Workflows: Enables structured collaboration among internal teams and vendors to review, annotate, and approve artwork efficiently.
Regulatory Compliance & Audit Logs: Supports global standards like FDA 21 CFR Part 11, with built-in version control and audit trails for traceability and inspection readiness.
Artwork Inspection Tools: Includes comparison and markup tools to verify graphics, barcodes, Braille, and text across artwork versions for compliance accuracy.
Centralized Asset & Content Management: Manages all artwork files and text content in a secure DAM system, ensuring consistency and reducing copy-related errors.
8. Smartflow by Loftware
Loftware Smartflow is a cloud-based artwork management platform that streamlines the packaging lifecycle by automating workflows, centralizing content, and ensuring regulatory compliance.
It offers tools for collaborative review, version control, and multilingual content management, helping organizations accelerate time-to-market while maintaining accuracy and consistency.
Key Features
Online Proofing & Review: Allows stakeholders to review and annotate artwork directly in the browser using high-resolution tools, improving accuracy and collaboration.
Version Control & Audit Trails: Tracks all changes and approvals throughout the artwork lifecycle to support traceability and regulatory audits.
Compliance & Validation Tools: Includes built-in validation features to ensure artwork meets regulatory standards and supports ongoing compliance.
Digital Asset & Phrase Management: Centralizes artwork files and multilingual copy in a structured library to maintain consistency and reduce translation errors.
9. Manage Artworks
ManageArtworks is a cloud-based artwork and labeling management platform streamlining packaging processes for regulated industries like pharmaceuticals, food, and consumer goods.
It centralizes content creation, approval workflows, and compliance checks to help brands reduce errors, accelerate time-to-market, and maintain regulatory standards.
Key Features
Streamlined Approval Process: Connects teams, agencies, and printers in a shared platform to review and approve artwork efficiently, reducing errors and delays.
AI-Powered Proofing: Uses automated tools to check artwork accuracy and manage revisions, ensuring only compliant versions progress through the workflow.
Regulatory Compliance & Brand Consistency: Supports adherence to industry regulations while maintaining consistent branding across products and markets.
Workflow Automation: Speeds up the artwork lifecycle by minimizing review cycles and enabling faster, more efficient product launches.
10. Ziflow
Ziflow is an online proofing platform that facilitates design and artwork approval processes by providing tools for collaborative review, annotation, and version control.
It supports compliance efforts through features like audit trails, customizable workflows, and role-based permissions, ensuring that creative assets meet regulatory and brand standards.
Key Features
Audit Trails for Compliance: Logs comments, approvals, and actions to support regulatory requirements like FDA CFR Part 11.
Annotation & Feedback Tools: Enables precise input from stakeholders to reduce rework and ensure artwork meets compliance and quality standards.
Automated Workflows & Notifications: Streamlines review cycles and enforces approval steps with automated routing and deadline alerts.
Role-Based Access Control: Secures artwork projects with user permissions, 2FA, and IP restrictions to protect sensitive data and maintain compliance.
11. GoVisually
GoVisually is an online proofing platform that streamlines design and artwork approval processes by enabling centralized feedback, version control, and real-time collaboration.
Its features, such as annotation tools and customizable workflows, support compliance efforts by ensuring that creative assets meet regulatory and brand standards.
Key Features
Automated Approval Workflows: Uses checklists and routing to verify that all required label elements are reviewed and approved, reducing compliance errors.
Audit Trails & Change Tracking: Logs every comment, update, and approval for full transparency and regulatory readiness.
Global Approvals & Role-Based Access: Supports multi-market feedback with permissions to ensure the right stakeholders review artwork at the right stage.
Precision Review Tools: Offers high-resolution zoom and side-by-side comparisons to catch detail-sensitive issues like ingredients, barcodes, and regulatory text.
12. 4Pack
4Pack is a cloud-based artwork and packaging management platform that streamlines the entire label and artwork lifecycle, from initial design to final approval and printing.
It offers centralized workflows, version control, and compliance tools to help brands in regulated industries reduce errors, accelerate time-to-market, and maintain regulatory standards.
Key Features
Integrated Artwork & Specs: Links artwork to up-to-date product specifications, reducing errors and supporting accurate, compliant packaging.
Collaborative Review Workflows: Enables controlled feedback and approvals with full visibility, ensuring artwork meets internal and regulatory standards.
Traceability & Audit Trails: Captures all changes and approvals to support compliance audits and maintain accountability.
Centralized Asset Management: Stores artwork files in a secure repository to ensure consistent use of approved, compliant assets across teams.
Improving Label and Artwork Approval with Signify
Signify helps manufacturers keep pace with changing packaging and labeling regulations by streamlining the entire compliance process.
Whether you're updating labels to reflect new global requirements or preparing for a marketplace audit, its AI-driven tools simplify artwork compliance so you can stay confident and on schedule.
What you’ll gain with Signify’s AI-powered compliance:
Faster Label Approvals: Cut down review time by automatically checking labels for regulatory compliance before they go to print.
Fewer Costly Errors: Identify issues like missing allergens, layout violations, or non-compliant claims early in the design stage.
Simplified Audit Readiness: Keep all your compliance documentation organized and easy to retrieve by product and region.
Real-Time Regulatory Updates: Stay informed with alerts tailored to your product category, so you never miss a critical change in FDA or global requirements.
Confidence in Every Launch: If a compliance issue is flagged, get clear, actionable steps to fix it, reducing the risk of delays or recalls.
Try Signify today to see how AI can help you validate design and artwork, manage documentation, and stay ahead of regulations, without slowing down your operations.
